Collagen-Based Sealants Market - Forecast(2023 - 2028)

Collagen-Based Sealants Market Overview

The global collagen-based sealants market size is estimated to reach US$1.9 billion by 2027 after growing at a CAGR of around 6.5% from 2022 to 2027. The collagen is the protein in the body parts which includes teeth, blood vessels, corneas, and others. The fibroblast secretes the collagen proteins for recovering and maintaining the tissue framework. The collagen sealant is pH stable, highly biocompatible, non-toxic, and easily absorbable. It has major applications in medical adhesives, wound treatment, dental implant treatments, cartilage repairs, and others. The increasing demand of collagen-based sealants and polyethylene glycol agents for post-operation and surgeries is driving the global collagen-based sealants market. Moreover, the rising applications of collagen-based sealants in hospitals, clinics, dental, and other end-use industries will offer high growth for the global collage-based sealants industry during the forecast period.

Collagen-Based Sealants Market COVID-19 Impact

The global collagen-based sealants market was majorly impacted by the global covid-19 pandemic. The pandemic created major economic shutdowns, demand and supply gap, logistics disruptions, and declining demand. The collagen-based sealants have major applications in hospitals, surgeries, and clinics. The hospital sector was affected by the pandemic disruptions in the initial covid phase. The worldwide lockdown disturbed the global hospital and medical sector. Moreover, various surgery centers, hospital units, and wound care and treatment services were delayed. The hospitals saw a shortage of beds, care professionals, medical equipment, others. According to the United States Census Bureau, the revenues of medical and diagnostic laboratories saw a fall of 10.9% in the 2^nd quarter of 2020. Thus, with disturbed medical and hospital sector in the initial phase of covid-19, the applications of collage-based sealants in medical adhesives, vascular grafts, implants, cartilage repair, and others declined, thereby led to a slowdown in the growth of global collagen-based sealants industry.

Report Coverage

The “Global Collagen-Based Sealants Market Report – Forecast (2022-2027)” by IndustryARC covers an in-depth analysis of the following segments of the global collagen-based sealants industry.

Key Takeaways

• The global collagen-based sealants market size will grow due to rise in demand across various end-use industries such as hospitals, orthopedic clinics, surgical centers, and others during the forecast period.
• North America holds the largest market share owing to the rise in healthcare, infrastructure, hospitals, surgeries, and advanced facilities, thereby boosting the demand of collagen-based sealants.
• The growing dental implants treatment will boost the growth prospects for collagen sealants owing to its rising demand in oral care and biocompatibility, tissue repair, and non-toxic features.

Collagen-Based Sealants Market Segment Analysis – By Application

By application, the wound treatment segment held the largest global collagen-based sealants market share and will grow at a CAGR of 6.7% during the forecast period. The demand of collage-based sealants is high for wound treatment applications in hospitals, surgeries, and orthopedic clinics. The collagen-based sealant attracts the fibroblasts in order to boost the collagen deposition to the wound. Moreover, the collagen-based sealants are also increasingly used in the surgical wound treatment owing to its biocompatibility, non-toxicity, and tissue regeneration properties. According to the Journal of the Australian Institute of Health and Welfare, approx. 11 million hospitalization cases were reported in the year 2019-2020. The excellent tissue regeneration and bone repair, and wound treatment post operations, and healing use of collagen-based sealants, along with polyethylene glycol in surgical centers, hospitals, and others is creating high demand in the market. Thus, the global collagen-based sealants industry will grow with high demand for wound treatment and care applications during the forecast period.

Collagen-Based Sealants Market Segment Analysis- By End-User

By end user, the hospital segment held the largest global collagen-based sealants market share and will grow at a CAGR of around 5.9% during the forecast period. The collagen-based sealants have major applications in the hospitals for surgeries, post-operation treatment, dental implants, and others. The tissue regenerative abilities, biocompatibility, stable pH, and non-toxicity properties makes it ideal for applications in the hospital segment. The collagen-based sealants are ideal choice for wound care and closures, bleeding control, and adhesion prevention. According to the World Bank, (WHO health expenditure database), the global health expenditure accounted for 9.8% of the GDP in 2019. Moreover, the rising demand of collagen-based sealants for surgeries, medical adhesives, post-operative, and wound treatment application in hospitals is offering growth in the market. Thus, with growing application of collagen-based sealants in the hospital end-use sector, the global collagen-based sealants market will grow during the forecast period.

Collagen-Based Sealants Market Segment Analysis – By Geography

By geographical analysis, the North America held the largest market share and is expected to grow at 31% in the global collagen-based sealants market during the forecast period. The increasing demand of collagen sealants in this region is influenced by rise in surgical procedures and developed hospital infrastructure, and clinics growth. The collagen-based sealants have application in collagen scaffolds, which is used for the cartilage repair and regeneration use in the clinics. Furthermore, the growth in hospital, surgical centres, and medical associations is driving the market of global collagen-based sealants. According to the Centre for Medicare & Medicaid Services (CMS), the United States government made a national expenditure of around USD 4.1 trillion in 2020. Moreover, the rising applications of collage-based sealants for tissue regeneration, dental implants, sports & medicines, and cardiovascular treatments are creating high demand in the market. Thus, with growing medical and surgical applications in the North American region, the global collagen-based sealants market will grow during the forecast period.

Collagen-Based Sealants Market Drivers

Rising demand from the dental care sector

The demand for collagen-based sealants in the dental care sector is rising due to growing applications in dental plugs, implants, bleeding control, and others. The collagen sealants are used in the dental industry for applications in tissue regeneration, dental surgeries, tooth extraction, teeth restoration, and others. The collagen-based sealants market is experiencing a drive with the high demand in dentistry and dental treatment applications. For instance, the MyDentalPlan Healthcare made the announcement of adding around 4000 clinics in India, thereby boosting the reach to around 250 cities in 2021. Furthermore, the growth of collagen-based sealants owing to its biocompatibility and non-toxicity for dental implants and dentistry end user is offering major growth opportunities for the global collagen-based sealants industry.

Growing demand in the orthopedic sector

The collagen-based sealants have major application in the orthopedic sector. It is used in bone graft substitutes, bone regeneration, tendon repair cartilage repair, and others. The osteoblasts are the fibroblasts that are used for bone formation through secretion of the organic components such as collagen for the bone matrix. Furthermore, the collagen sealants are used with the biomaterials in order to encourage fast cell growth and tissue regeneration. According to the International Osteoporosis Foundation (IOF), the orthopedic device sector is expected to grow by around USD 67 million by the year 2030. Moreover, the increasing application of collagen-based sealants in bone surgeries, grafts, and others is creating drive in the market and offering major growth opportunities in the global collagen-based sealants industry.

Collagen-Based Sealants Market Challenges

Substitute threats and availability of biomaterial alternatives

The collagen based sealants have high demand in the hospitals, clinics surgery centers, and others. However, the availability of substitute biomaterials alternative is creating a major challenge in the market. The biomaterials such as polylactic-co-glycolic acid (PLGA), hyaluronic acid, chitosan, polyglycolic acid, and others offer high efficiency and reliability in tissue regeneration, repair, and healing. The growing usage of these biomaterials as an alternative to collagen is restricting the growth opportunities in the global collagen-based sealants industry, thereby leading to slowdown in the market.

Collagen-Based Sealants Industry Outlook

The global collagen-based sealants top 10 companies include:

1. Adhesives Research Inc
2. Cohera Medical Inc.
3. HemCon Medical Technologies Inc
4. CryoLife Inc.
5. Baxter International Inc.
6. Advanced Medical Solutions Group Plc
7. Johnson & Johnson
8. Kerr Corporation
9. 3M Company
10. Dentsply Sirona Inc.

Recent Developments

• In December 2021, the BD company sealed the deal to acquire the self-adhesive surgical sealant business of the Tissuemed, with the aim to boost the portfolio and expand the surgical offerings across the world.
• In December 2019, the CryoLife Inc. entered into partnership with the Misonic for the commercialization of the NeoPatch product of the CryoLife with the aim to treat indications of the vascular and cardiac surgeries.
• In January 2019, Advanced Medical Solutions Group plc, a leading firm in collagen-based sealants and wound care specialists acquired the Sealantis Limited in around USD 25 million with the aim to boost the high-margin intensive internal surgery.

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